News from the world of advanced treatments

Mezenhimske matične celice-nosilci endogene regenerativne sposobnosti tkiv v boju proti staranju mišično-skeletnega sistema

raziskovalni program, ARIS, Fak.za farmacijo, Janja Zupan
30.6.2023

Dexamethasone-Integrated Mesenchymal Stem Cells for Systemic Lupus Erythematosus Treatment via Multiple Immunomodulatory Mechanisms

ACS Nano 2024, XXXX, XXX, XXX-XXX
Publication Date:May 8, 2024

Me2SO- and serum-free cryopreservation of human umbilical cord mesenchymal stem cells using electroporation-assisted delivery of sugars

Mutsenko V, Barlič A, Pezić T, Dermol-Černe J, Dovgan B, Sydykov B, Wolkers WF, Katkov II, Glasmacher B, Miklavčič D, Gryshkov O.
Cryobiology. 2019 Dec; 91:104-114.

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Combination of Filtered Bone Marrow Aspirate and Biomimetic Scaffold for the Treatment of Knee Osteochondral Lesions: Cellular and Early Clinical Results of a Single Centre Case Series

Veber M, Vogler J, Knežević M, Barlič A, Drobnič M.
Tissue Eng Regen Med. 2020 Jun; 17(3): 375–386.

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Human mesenchymal stromal cells from different tissues exhibit unique responses to different inflammatory stimuli

Burja B, Barlič A, Erman A, Mrak-Poljšak K, Tomšič M, Sodin-Semrl S, Lakota K.
Curr Res Transl Med. 2020 Nov; 68(4):217-224.

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Intracellular delivery of trehalose renders mesenchymal stromal cells viable and immunomodulatory competent after cryopreservation

Dovgan B, Miklavčič D, Knežević M, Zupan J, Barlič A.
Cytotechnology. 2021 Apr; 73 (3):1–21.

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Autologous chondrocytes versus filtered bone marrow mesenchymal stem/stromal cells for knee cartilage repair-a prospective study

Martinčič D, Leban J, Filardo G, Busacca M, Barlič A, Veber M, Drobnič M.
Int Orthop. 2021 Apr;45(4):931-939.

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Compassionate mesenchymal stem cell treatment in a severe COVID-19 patient: a case report

Primorac D, Stojanović Stipić S, Strbad M, Girandon L, Barlič A, Frankić M, Ivić I, Marasović Krstulović D, Jukić I, Halassy B, Hećimović A, Matišić V, Molnar V.
Croat Med J. 2021 May; 62.

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Intraoperative intradermal application of stromal vascular fraction into the abdominal suture line: histological analysis of abdominal scar tissue

Živec K, Veber M, Pizem J, Jež M, Božikov K, Švajger U.
Aesthetic Plastic Surgery. 2022 Dec; 46: 2853–2862.

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Gene expression of cultured human chondrocytes as a model for assessing neutralization efficacy of soluble TNFα by TNFα antagonists.

Barlič A, Žigon S, Blejec A, Kregar Velikonja N
Biologicals. 2015 May;43(3):171-80.

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Autologous Mesenchymal Stem Cells for Treatment of Chronic Active Antibody-Mediated Kidney Graft Rejection: Report of the Phase I/II Clinical Trial Case Series

Večerić-Haler Ž, Sever M, Kojc N, Halloran PF, Boštjančič E, Mlinšek G, Oblak M, Poženel P, Švajger U, Hartman K, Kneževič M, Barlič A, Girandon L, et al.
Transpl Int. 2022 Nov 22; 35: 10772.

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Perinatal derivatives application: Identifying possibilities for clinical use

Gindraux F, Hofmann N, Agudo-Barriuso M, Antica M, Couto PS, Dubus M, Forostyak S, Girandon L, et. al.
Front Bioeng Biotechnol. 2022 Oct 11; 10: 977590.

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Treatment of Pulmonary Sarcoidosis Using Allogenic Bone Marrow-Derived Mesenchymal Stem Cell Therapy is Safe: A Case Report

Pavelić E, Matišić V, Molnar V, Brlek P, Pavlovic T, Strbad M, Girandon L, Knežević M, Primorac D.
Int J Med Sci Clin Res. 2022 Jun; 2(6): 512-515.

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Treatment of Severe Steroid-Refractory Acute-Graft-vs.-Host Disease With Mesenchymal Stem Cells-Single Center Experience

Česen Mazič M, Girandon L, Kneževič M, Avčin SL, Jazbec J.
Front Bioeng Biotechnol. 2018 Jul 24;6:93.

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Hematopoietic stem cell and mesenchymal stem cell population size in bone marrow samples depends on patient’s age and harvesting technique

Rebolj K, Veber M, Drobnič M, Maličev E.
Cytotechnology. 2018 Dec; 70(6): 1575–1583.

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Survival Rates of Various Autologous Chondrocyte Grafts and Concomitant Procedures. A Prospective Single-Center Study over 18 Years

Martinčič D, Mekač J, Drobnič M.
Cell Transplant. 2019 Nov; 28(11): 1439–1444.

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The outcome of autologous chondrocyte transplantation treatment of cartilage lesions in the knee

Drobnic M, Kregar-Velikonja N, Radosavljevic D, Gorensek M, Koritnik B, Malicev E, Wozniak G, Jeras M, Knezevic M.
Cell Mol Biol Lett. 2002; 7(2):361-3.

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Nucleus pulposus repair with cultured autologous elastic cartilage derived chondrocytes

Gorensek M, Jaksimović C, Kregar-Velikonja N, Gorensek M, Knezevic M, Jeras M, Pavlovcic V, Cör A.
Cell Mol Biol Lett. 2004;9(2):363-73.

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Tissue formation following implantation of cultured elastic chondrocytes for treatment of vesicoureteral reflux

Kregar-Velikonja N, Coer A, Gorensek M, Knezević M, Kmetec A.
Nephrol Dial Transplant. 2008 Feb;23(2):764-6.

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Quantitative analysis of gene expression in human articular chondrocytes assigned for autologous implantation

Barlic A, Drobnic M, Malicev E, Kregar-Velikonja N.
J Orthop Res. 2008 Jun;26(6):847-53.

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Growth and differentiation of alveolar bone cells in tissue-engineered constructs and monolayer cultures

Malicev E, Marolt D, Kregar Velikonja N, Kreft ME, Drobnic M, Rode M.
Biotechnol Bioeng. 2008 Jul 1;100(4):773-81.

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Comparison of articular and auricular cartilage as a cell source for the autologous chondrocyte implantation

Malicev E, Kregar-Velikonja N, Barlič A, Alibegović A, Drobnic M.
J Orthop Res. 2009 Jul;27(7):943-8.

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Bone tissue engineering with human stem cells

Marolt D, Knezevic M, Novakovic GV.
Stem Cell Res Ther. 2010 May 4;1(2):10.

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Cartilage from the edge of a debrided articular defect is inferior to that from a standard donor site when used for autologous chondrocyte cultivation

Malicev E, Barlič A, Kregar-Velikonja N, Stražar K, Drobnič M.
J Bone Joint Surg Br. 2011 Mar;93(3):421-6.

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In vitro models for adipose tissue engineering with adipose-derived stem cells using different scaffolds of natural origin

Girandon L, Kregar-Velikonja N, Božikov K, Barlič A.
Folia Biol (Praha). 2011;57(2):47-56.

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Primary human alveolar bone cells isolated from tissue samples acquired at periodontal surgeries exhibit sustained proliferation and retain osteogenic phenotype during in vitro expansion

Marolt D, Rode M, Kregar-Velikonja N, Jeras M, Knezevic M.
PLoS One. 2014 Mar 25;9(3): e92969.

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Cell sources for nucleus pulposus regeneration

Kregar Velikonja N, Urban J, Fröhlich M, Neidlinger-Wilke C, Kletsas D, Potočar U, Turner S, Roberts S.
Eur Spine J 23, 364–374 (2014).

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Ten-year clinical and radiographic outcomes after autologous chondrocyte implantation of femoral condyles

Martinčič D, Radosavljevič D, Drobnič M.
Knee Surg Sports Traumatol Arthrosc. 2014 Jun;22(6):1277-83.

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Adipose-Derived Stem Cells Respond to Increased Osmolarities

Potočar U, Hudoklin S, Kreft ME, Završnik J, Božikov K, Fröhlich M.
PLoS One. 2016 Oct 5;11(10): e0163870.

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Nanocellulose-Based Interpenetrating Polymer Network (IPN) Hydrogels for Cartilage Applications

Naseri N, Deepa B, Mathew AP, Oksman K, Girandon L.
Biomacromolecules. 2016 Nov 14;17(11):3714-3723.

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Pro-myogenic and low oxygen culture increases expression of contractile smooth muscle markers in human fibroblasts

Veber M, Dolivo D, Rolle M, Dominko T.
J Tissue Eng Regen Med. 2018 Mar; 12(3): 572-582.

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