Chronic wounds are a stubborn problem that plagues more and more people around the world, from diabetics who are dealing with long-term ulcers, to the elderly where slow wound healing is becoming a more common problem. Traditional methods of treatment often do not bring the desired results, which makes it imperative to search for more effective solutions.
Here come the mesenchymal stem or stromal cells (MSCs), which bring a breath of fresh air in the fight against chronic wounds. MSCs are miracle workers in our body, not only do they promote tissue regeneration, but they also calm inflammation, which is often present in chronic wounds. They work by secreting various molecules that "talk" to the cells in the wound, activate them and stimulate more effective healing.
In diabetics struggling with diabetic foot and incurable ulcers, with the use of MSC therapy, we can achieve that wounds start to heal faster, pain is reduced, and patients can finally return to an active life without constant worry and pain.
Therefore, when it comes to treating chronic wounds, not all methods are the same. By choosing treatment with MSCs, patients can not only improve their current condition but also significantly increase their quality of life. And that's the charm and power of this promising therapy - in its ability not only to heal wounds but also to heal life.
MSC are multipotent cells that can differentiate into mesodermal cell lineages, such as adipocytes, osteocytes, and chondrocytes. MSC were initially isolated from bone marrow, but it is now known that they are found in almost all tissues (e.g., adipose tissue, umbilical cord, etc.). MSC have the ability to migrate to the site of injury in the body, where they can differentiate and replace damaged cells, as well as promote tissue regeneration. Additionally, they have the capacity for paracrine signaling and cell-to-cell communication by secreting various soluble factors and extracellular vesicles. In an inflammatory environment, they act immunomodulatory on different cells of the innate and adaptive immune systems, which is one of their main properties exploited for therapeutic purposes.
They can be used for local tissue regeneration or for their systemic effects.
It is important to know that PRP treatment is not the same as our therapy. PRP treatment uses only 1 to 3 stem cells, while our therapy uses a dosed amount of 15 to 20 million stem cells.
We at GaiaCell are a biotechnology company specialized in safe and effective cell therapies in orthopedics, hematooncology, pulmonology and other therapeutic areas. Our high-tech laboratories with GMP certificate and research center guarantee the highest quality and innovation. We also offer contract development and manufacturing (CDMO), ensuring top-notch project execution.