Chronic inflammatory diseases of the digestive tract are an important area where treatment with mesenchymal stem cells (MSCs) can bring great benefits. These cells have a unique ability to help the body manage inflammatory processes and promote the regeneration of damaged tissue.
For example, individuals suffering from inflammatory bowel disease, such as Crohn's disease, can MSCs help reduce inflammation in the intestines and accelerate the healing of ulcers. Similarly, in people with ulcerative colitis, MSCs can help in the regeneration of damaged intestinal tissue, which can reduce disease symptoms such as bleeding, diarrhea, and pain.
MSC are multipotent cells that can differentiate into mesodermal cell lineages, such as adipocytes, osteocytes, and chondrocytes. MSC were initially isolated from bone marrow, but it is now known that they are found in almost all tissues (e.g., adipose tissue, umbilical cord, etc.). MSC have the ability to migrate to the site of injury in the body, where they can differentiate and replace damaged cells, as well as promote tissue regeneration. Additionally, they have the capacity for paracrine signaling and cell-to-cell communication by secreting various soluble factors and extracellular vesicles. In an inflammatory environment, they act immunomodulatory on different cells of the innate and adaptive immune systems, which is one of their main properties exploited for therapeutic purposes.
They can be used for local tissue regeneration or for their systemic effects.
It is important to know that PRP treatment is not the same as our therapy. PRP treatment uses only 1 to 3 stem cells, while our therapy uses a dosed amount of 15 to 20 million stem cells.
We at GaiaCell are a biotechnology company specialized in safe and effective cell therapies in orthopedics, hematooncology, pulmonology and other therapeutic areas. Our high-tech laboratories with GMP certificate and research center guarantee the highest quality and innovation. We also offer contract development and manufacturing (CDMO), ensuring top-notch project execution.